- Ornithine Decarboxylase-1 (ODC-1) Antibody
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- MBS4381136
- 0.5 mL
- Monoclonal
- Human
- Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format
- Flow Cytometry (FC/FACS), Immunofluorescence (IF)
- Mouse
- 53kDa
- Ornithine Decarboxylase-1 (ODC-1)
- Purified Ab conjugated to CF488
- ornithine decarboxylase 1
- ODC
- Unconjugated
- IgG1 kappa
- ODC1/485
Specifications/Features
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa